Research for Science Art and Technology (RFSAT) Limited

HORIZON Europe "ENACT" (GAP-101157151)

"Environmental Effect on Health Care and Wellbeing and Active Interventions"

Funding program: HORIZON.2.1.2 - Environmental and Social Health Determinants

Focus area: Building a low-carbon, climate resilient future (LC)

Topic: HORIZON-HLTH-2024-ENVHLTH-02-two-stage

Funding instrument: HORIZON-RIA - HORIZON Research and Innovation Actions

Coordinator: Alliance for IOT and Edge Computing Innovation (AIOTI)

Time frame: 1 January 2025 - 30 June 2028

Non-communicable diseases (NCDs) account for 80% of the disease burden as well as for the majority of premature deaths in the EU; diminishing the citizens’ quality of life, life expectancy and increasing the financial burden (from those affected to the health system). During the last 3 decade environmental stressors have been addressed through numerous studies, which have raised concerns about the detrimental effects of the environment on human health. Most evaluated environmental stressors are air temperature, particulate and gaseous air pollutants, urban noise, food pollutants and radiation.

By end of 2022, air pollution was reported to be responsible of an excess mortality of 311.000 people per year in the UE-27 , driving not only premature deaths but also an increased risk of vascular diseases such as ischemic heart disease, stroke, and other non-communicable non-vascular diseases like chronic respiratory diseases or depression. Some newly considered stressors such as electromagnetic field, and light exposure are also susceptible to affect human health (e.g. ocular and dermatological NCD diseases).

ENACT aims at building a pathway to generate clinical, technological and economic short & long-term impact targeting local and regional stakeholders and create impact by: Developing a state-of-the-art environmental risk score and analyzer driven framework and platform to predict, monitor and prevent the exposomic risk of acute and chronic health conditions of chronic vascular and non-vascular NCDs.

This new exposomic risk score and analyzer will support:

  • patients
  • health professionals/hospitals
  • policy makers

ENACT aims at reducing the human and financial burden of NCD, considering potential individual vulnerability factors, and reinforcing both a clinical and a policy implementation that enables prevention and disease management for higher quality of life..

WEB Portals:

Example Developments:

Example data from in-situ environmental sensor: https://rfsat.com/projects/HORIZON-ENACT/ThingSpeakViewer.html

This sensors currently supports:

  • NO, NO2, SO2, CO, 4H2S and O3 parameters.

The indoor environmental sensor, built upon Raspberry PI-Zero and with ENVIRO+ gas sensor board:

This sensor node currently supports the following pollutants:

  • Particulate matter: PM1/PM2.5/PM10
  • Climate data: ambient temperature, humidity and barometric pressure
  • Air quality: TVOC, eCO2
  • Gas pollutants: CO, NO2, C2H5OH (ethanol), H2 (hydrogen), NH3 (ammonia), CH4 (methane), C3H8 (propane), C4H10 (iso-butane)
  • Visible light intensity
  • Noise level (MEMS microphone).

 

Latest news:

ENACT Project HE turns the exposomic approach into operational tools for health and policy. ENACT consortium met in Brussels in mid-February 2026 to agree next steps of the framework implementation into concrete, interoperable outputs. At the core of ENACT is the exposomic approach integrating environmental, lifestyle, and biological exposures across the life course, and linking them to non-communicable disease (NCD) outcomes. For more infomation refer to the ENACT post on LinkedIn